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RD Department

 

 
 
 
 
 

 

 



Positions Available in Cyto-Pharm, Inc.

Cyto-Pharm is a process development company dedicated to produce human natural cytokines, including interferon. Its core technology platform and the human cell lines are under protection by 19 multi-national patents. Cytokines derived from human cells overmatch their recombinant counter parts produced in prokaryotic or other eukaryotic systems since they show proper post-translational modification and correct protein folding. Another advantage demonstrates that human natural proteins have lower side effect and better efficacy in the clinical applications. Although the manufacturing of bacterial recombinant proteins is still the mainstream in protein drug industry, the production technology for the natural forms will prevail in the future, thanks to the states of art on cell line development of strong interests as well as bioreactor operation with optimal control. We currently have 20 staff members and plan to triple the size of 60 in the coming year. We are sincerely inviting persons who possess Ph.D., Master or Bachelor degree with the essential expertise to join the following fields:

(01) Animal Cell culturing (cell suspension or/and adherent) - cell banking, cell sorting/screening, serum free adaptation, spinner bioreactors, viral induction, anti-viral assays, Flow Cytometry, cell culture lab management.
(02) Protein Over-expression in Human Cells– viral or non-viral vector construction and maximization for mammalian systems, RNAi technique, transfection and transformation, quantification techniques for gene expression; High-Through-Put Screening.
(03) Biochemical Engineering–operation and optimization for small-, pilot- or industrial scales of bioreactors (including roller bottles or cell factories) for animal cell cultures, knowing process design is preferred; large cell culture concentration and recovery techniques.
(04) Protein Purification – must be familiar with various column chromatography techniques for FPLC and HPLC; knowing process design for purifying new protein targets is preferred.
(05) Protein Assays – development for in-house qualification and quantification assays using (A) immuno-techniques such as ELISA etc., (B) HPLC profiling and LC-Mass (-Mass) techniques.
(06) Protein Drugs Formulation – must know the FDA regulation to generate legally accepted formulations for protein drug storage and for stability evaluation.
(07) Animal Toxicity –with experience of conducting / coordinating GLP level pre-clinical pharmacology / toxicology studies such as genotoxicity, acute toxicity, chronic toxicity, pharmacokinetic studies and pharmacology studies etc.
(08) Clinical Research –with experience of conducting / coordinating ICH-GCP standard clinical studies. Experience in early phase studies (phase I or phase I/II) is preferred.
(09) QA/QC –with experience of performing quality assurance / quality control in pharmaceutical industry. Good at document management and SOP writing / maintenance.
(10) Regulatory Affairs – must be familiar with FDA regulations of biological products and medical devices, 2 years experience with good communication skill in English is preferred.

Please send cover letter which describes the fields of interest, Curriculum vitae and two reference letters to the following address:

Secretary to President
Cyto-Pharm, Inc.
6F, No. 6, Sec.1, Jungshing Rd.,
Wugu, Taipei County, 248 Taiwan

Email : careers@cyto-pharm.com

 
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