賽德醫藥科技股份有限公司徵才啟事

本公司擁有多國專利的人類細胞株與技術平台以生產天然細胞激素 (Cytokines) 包括干擾素 (Interferons)。由於必要的蛋白質轉譯後修飾(Essential Post-translational Modification)與正確的蛋白質折疊 (Correct Protein Folding)扮演關鍵的角色，以及伴隨副作用的減低，由人類細胞株生產之細胞激素在治療病毒感染與對抗癌細胞增生的效力上絕對優於細菌與其他真核細胞生產的重組蛋白。雖然後者仍是醫藥市場上的主流，然而隨著生產技術的提升，大規模培養人類細胞以純化目標蛋白質將會是下一波蛋白質製藥產業的主流。我們在此竭誠邀請有興趣與經驗之人士加入我們研究產程發展行列。目前我們已有20位員工，將在一年內增至60位。凡具國內外博、碩與學士學位而且有產業界或研究單位經驗並擁有下列專業者均為優先考慮的對象：

(01)	Animal Cell culturing (cell suspension or/and adherent) - cell banking, cell sorting/screening, serum free adaptation, spinner bioreactors, viral induction, anti-viral assays, Flow Cytometry, cell culture lab management.
(02)	Protein Over-expression in Human Cells– viral or non-viral vector construction and maximization for mammalian systems, RNAi technique, transfection and transformation, quantification techniques for gene expression; High-Through-Put Screening.
(03)	Biochemical Engineering–operation and optimization for small-, pilot- or industrial scales of bioreactors (including roller bottles or cell factories) for animal cell cultures, knowing process design is preferred; large cell culture concentration and recovery techniques.
(04)	Protein Purification – must be familiar with various column chromatography techniques for FPLC and HPLC; knowing process design for purifying new protein targets is preferred.
(05)	Protein Assays – development for in-house qualification and quantification assays using (A) immuno-techniques such as ELISA etc., (B) HPLC profiling and LC-Mass (-Mass) techniques.
(06)	Protein Drugs Formulation – must know the FDA regulation to generate legally accepted formulations for protein drug storage and for stability evaluation.
(07)	Animal Toxicity –with experience of conducting / coordinating GLP level pre-clinical pharmacology / toxicology studies such as genotoxicity, acute toxicity, chronic toxicity, pharmacokinetic studies and pharmacology studies etc.
(08)	Clinical Research –with experience of conducting / coordinating ICH-GCP standard clinical studies. Experience in early phase studies (phase I or phase I/II) is preferred.
(09)	QA/QC –with experience of performing quality assurance / quality control in pharmaceutical industry. Good at document management and SOP writing / maintenance.
(10)	Regulatory Affairs – must be familiar with FDA regulations of biological products and medical devices, 2 years experience with good communication skill in English is preferred.

有意者請備妥首頁信(cover letter)敘述申請專長(可多項)，自傳與履歷表內述目前待遇與希望待遇，逕寄 (電郵以 MS Word 檔):

總經理秘書
賽德醫藥技術股份有限公司
台北縣五股鄉中興路一段6號6樓 (電郵:careers@cyto-pharm.com )