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赛德医药科技股份有限公司征才启事

本公司拥有多国专利的人类细胞株与技术平台以生产天然细胞激素 (Cytokines) 包括干扰素 (Interferons)。由于必要的蛋白质转译后修饰(Essential Post-translational Modification)与正确的蛋白质折迭 (Correct Protein Folding)扮演关键的角色,以及伴随副作用的减低,由人类细胞株生产之细胞激素在治疗病毒感染与对抗癌细胞增生的效力上绝对优于细菌与其它真核细胞生产的重组蛋白。虽然后者仍是医药市场上的主流,然而随着生产技术的提升,大规模培养人类细胞以纯化目标蛋白质将会是下一波蛋白质制药产业的主流。我们在此竭诚邀请有兴趣与经验之人士加入我们研究产程发展行列。目前我们已有20位员工,将在一年内增至60位。凡具国内外博、硕与学士学位而且有产业界或研究单位经验并拥有下列专业者均为优先考虑的对象:

(01) Animal Cell culturing (cell suspension or/and adherent) - cell banking, cell sorting/screening, serum free adaptation, spinner bioreactors, viral induction, anti-viral assays, Flow Cytometry, cell culture lab management.
(02) Protein Over-expression in Human Cells– viral or non-viral vector construction and maximization for mammalian systems, RNAi technique, transfection and transformation, quantification techniques for gene expression; High-Through-Put Screening.
(03) Biochemical Engineering–operation and optimization for small-, pilot- or industrial scales of bioreactors (including roller bottles or cell factories) for animal cell cultures, knowing process design is preferred; large cell culture concentration and recovery techniques.
(04) Protein Purification – must be familiar with various column chromatography techniques for FPLC and HPLC; knowing process design for purifying new protein targets is preferred.
(05) Protein Assays – development for in-house qualification and quantification assays using (A) immuno-techniques such as ELISA etc., (B) HPLC profiling and LC-Mass (-Mass) techniques.
(06) Protein Drugs Formulation – must know the FDA regulation to generate legally accepted formulations for protein drug storage and for stability evaluation.
(07) Animal Toxicity –with experience of conducting / coordinating GLP level pre-clinical pharmacology / toxicology studies such as genotoxicity, acute toxicity, chronic toxicity, pharmacokinetic studies and pharmacology studies etc.
(08) Clinical Research –with experience of conducting / coordinating ICH-GCP standard clinical studies. Experience in early phase studies (phase I or phase I/II) is preferred.
(09) QA/QC –with experience of performing quality assurance / quality control in pharmaceutical industry. Good at document management and SOP writing / maintenance.
(10) Regulatory Affairs – must be familiar with FDA regulations of biological products and medical devices, 2 years experience with good communication skill in English is preferred.

有意者请备妥首页信(cover letter)叙述申请专长(可多项),自传与履历表内述目前待遇与希望待遇,径寄 (电邮以 MS Word 檔):

总经理秘书
赛德医药技术股份有限公司
台北县五股乡中兴路一段6号6楼 (电邮:careers@cyto-pharm.com )

 
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